Micro TESE

Micro-TESE is a surgical procedure used in the treatment of male infertility caused by sperm-related issues. In cases where azoospermia is diagnosed, Micro-TESE is performed to obtain sperm from the testis, enabling the individual to have children through the IVF method.

Micro TESE (Microdissection TESE): What Is It?

Micro TESE (Microdissection Testicular Sperm Extraction) is a micro-surgical procedure used to retrieve sperm from the testicles in men with azoospermia (no sperm in semen). It enables many men with zero sperm count to father a child through IVF/ICSI.
In rare cases of severe motility issues or high DNA fragmentation, Micro TESE may also be used to obtain healthier sperm cells.
This method provides hope for men who otherwise have no sperm detectable in their semen.

Why Can Sperm Be Absent in Semen?

Sperm absence may result from multiple underlying causes. The most common are:

  • Obstruction in sperm ducts
  • Undescended testes
  • Hormonal disorders
  • Congenital absence of sperm ducts
  • Medications
  • Genetic factors
  • Radiation exposure & chemotherapy
  • Past infections

In nearly half of azoospermia cases, no identifiable cause is found, yet Micro TESE may still offer a chance for fatherhood.

Can Men With Zero Sperm Become Fathers With Micro TESE?

Yes. Micro TESE is often the most effective method for sperm retrieval in men diagnosed with azoospermia. Since the tissue is examined under a microscope with up to 24x magnification, even tiny tubules containing limited sperm production can be detected, a major advantage over traditional biopsy techniques.
Many couples can achieve pregnancy using sperm retrieved during Micro TESE, provided the right surgical expertise and laboratory conditions are present.

How Is Micro TESE Performed?

The procedure is done under general anesthesia. A single incision is made in the testicle, and the tissue is examined microscopically to identify areas with sperm production potential. The selected tissue is carefully removed and processed in the embryology laboratory.
If live sperm is found and the eggs are ready, ICSI can be performed on the same day. Extra sperm cells may be frozen for future IVF cycles, preventing the need for repeated surgery.

Advantages of Micro TESE

Unlike conventional TESE, Micro TESE uses high-magnification surgery to protect tissue and increase sperm retrieval chances.
Main benefits include:

  • Higher sperm retrieval success compared to standard TESE
  • Minimal tissue damage and better hormone preservation
  • Lower complication rates with faster recovery
  • Allows sperm freezing for future IVF attempts
  • Can be repeated when medically necessary
  • Even in complex cases such as Klinefelter syndrome, Micro TESE can offer better outcomes.

Does Technology Affect Micro TESE Success?

Definitely. Micro TESE success depends heavily on the technology and equipment used.
A high-resolution surgical microscope is essential to clearly visualize blood vessels and sperm-producing tubules, helping the surgeon extract only necessary tissue instead of sampling randomly.
Equally important is the quality of micro-surgical instruments, which helps minimize trauma and speeds recovery.
On the laboratory side, advanced micromanipulation systems support sperm identification, selection, and freezing. The more advanced the laboratory infrastructure, the higher the likelihood of retrieving viable sperm cells.

Role of Surgeon Experience

Micro TESE is a highly delicate procedure, and outcomes depend strongly on the surgeon’s skill. An experienced surgeon can differentiate tissue more accurately under the microscope, avoid unnecessary damage, and improve the chance of sperm retrieval, especially in patients with previous failed biopsies.
Experience also matters in planning the operation, managing the post-operative process, and interpreting pathological results for repeat attempts.

How Long Does the Procedure Take?

Micro TESE typically takes 1–2 hours under general anesthesia.
Patients are monitored for a few hours afterward and usually return home the same day. A short resting period is needed, and full physical activity should be avoided for about 10 days.

Post-Procedure Care

Recovery is generally comfortable. However, patients should follow medical recommendations closely:

  • Avoid driving on the same day
  • Rest for 3–4 days and avoid heavy activity for 10 days
  • Dressing change is recommended after 48 hours
  • Shower can be taken 3 days later
  • Tight underwear or scrotal support is advised for 10–15 days
  • Stitches dissolve naturally within a week

How Many Times Can Micro TESE Be Repeated?

There is no fixed limit. Whether a repeat procedure is advisable depends on clinical evaluation, previous biopsy results, and pathology findings.
If sperm precursor cells are detected, repeating Micro TESE may still lead to success.

What If No Sperm Is Found?

If microdissection does not yield sperm, the collected tissue must undergo pathological evaluation. This guides future treatment decisions and may help determine whether a repeated Micro TESE is worth considering.

Micro TESE Cost

Due to legal regulations, pricing cannot be listed publicly.
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